Best friends Tully and Kate support each other through good times and bad with an unbreakable bond that carries them from their teens to their 40s.

An invisible and mysterious force field descends upon the small town of Chester's Mill, Maine, USA, trapping residents inside, cut off from the rest of civilization. The trapped townspeople must discover the secrets and purpose of the "dome" or "sphere" and its origins, while coming to learn more than they ever knew about each other and animals too.

After narrowly escaping a bizarre accident, a troubled teenager is plagued by visions of a man in a large rabbit suit who manipulates him to commit a series of crimes.